FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CHD4
反应性
Human
应用
WB,CoIP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
260kD
推荐稀释比
WB 1:1000;IP 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human CHD4 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of CHD4 and does not cross-react with related proteins.
基因名称
chd4
别名
ATP dependent helicase CHD4;ATP-dependent helicase CHD4;CHD 4;CHD-4;CHD4;CHD4_HUMAN;Chromodomain helicase DNA binding protein 4;Chromodomain-helicase-DNA-binding protein 4;DKFZp686E06161;Mi 2 autoantigen 218 kDa protein;Mi 2b;Mi-2 autoantigen 218 kDa protein;Mi2 beta;Mi2-beta.
Organism-1
Human
基因ID-1
1108
SwissProt-1
Q14839
Organism-2
Mouse
SwissProt-2
Q6PDQ2
背景
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
细胞定位
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with centrosomes in interphase. .
