- 产品信息
商品描述
靶点-Target
NRF-1
反应性
Human
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
72kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human TCF11/NRF1 protein fragments expressed in E.coli
特异性
This antibody detects endogenous levels of TCF11/NRF1 and does not cross-react with related proteins.
基因名称
nrf1
别名
alpha pal;alpha palindromic binding protein;Alpha palindromic-binding protein;Alpha-pal;locus control region factor 1;NFE2 related factor 1;NRF-1;Nrf1;NRF1_HUMAN;Nuclear respiratory factor 1;transcription factor 11.
Organism-1
Human
基因ID-1
4899
SwissProt-1
Q16656
Organism-2
Mouse
SwissProt-2
Q9WU00
背景
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014],
细胞定位
Nucleus.





