FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Hsp27
反应性
Human,Monkey
应用
WB,ICC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:1000;ICC 1:300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Hsp27 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Hsp27 and does not cross-react with related proteins.
基因名称
hspb1
别名
Heat shock 27kDa protein;28 kDa heat shock protein;CMT2F;DKFZp586P1322;Estrogen regulated 24 kDa protein;Estrogen-regulated 24 kDa protein;Heat shock 25kDa protein 1;Heat shock 27 kDa protein;Heat shock 27kD protein 1;Heat shock 27kDa protein 1;Heat shock 28kDa protein 1;Heat Shock Protein 27;Heat Shock Protein 27;Heat shock protein beta 1;Heat shock protein beta-1;HMN2B;HS.76067;Hsp 25;HSP 27;Hsp 28;Hsp B1;Hsp25;HSP27;Hsp28;HspB1;HSPB1_HUMAN;SRP27;Stress responsive protein 27;Stress-responsive protein 27.
Organism-1
Human
基因ID-1
3315
SwissProt-1
P04792
Organism-2
Mouse
SwissProt-2
P14602
背景
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008],
细胞定位
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. .
