- 产品信息
商品描述
靶点-Target
AKR1B1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human AKR1B1 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of AKR1B1 and does not cross-react with related proteins.
基因名称
akr1b1
别名
ADR;AKR1B 1;Akr1b1;Aldehyde reductase 1;Aldehyde reductase;Aldo keto reductase family 1, member B1;Aldo-keto reductase family 1 member B1;aldo-keto reductase family 1, member B1;aldose reductase;Aldose reductase;aldr 1;ALDR_HUMAN;ALDR1;ALR2;AR;Lii5 2 CTCL tumor antigen;Low Km aldose reductase;MGC1804.
Organism-1
Human
基因ID-1
24192
SwissProt-1
P15121
Organism-2
Mouse
SwissProt-2
P45376
背景
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009],
细胞定位
Cytoplasm.





