- 产品信息
商品描述
靶点-Target
RAB4A
反应性
Human,Mouse,Rat,Monkey
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human RAB4A protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of RAB4A and does not cross-react with related proteins.
基因名称
rab4a-n
别名
HRES 1 / RAB4;Oncogene RAB4;OTTHUMP00000042824;Rab 4;RAB 4A;RAB4 member RAS oncogene family;RAB4A;RAB4A member RAS oncogene family;RAB4A_HUMAN;Ras related protein Rab 4A;Ras related protein Rab4A;Ras-related protein Rab-4A.
Organism-1
Human
基因ID-1
5867
SwissProt-1
P20338
Organism-2
Mouse
SwissProt-2
P56371
背景
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012],
细胞定位
Membrane; Peripheral membrane protein . Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Recycling endosome membrane ; Peripheral membrane protein . Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1. .





