FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ATIC
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
64kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human ATIC protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of ATIC and does not cross-react with related proteins.
基因名称
atic
别名
5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase;5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase;5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase;5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase;AICAR;AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme;AICAR transformylase;AICARFT;AICARFT/IMPCHASE;ATIC;Bifunctional purine biosynthesis protein PURH;FLJ93545;IMP cyclohydrolase;IMP synthase;IMP synthetase;IMPCHASE;Inosinicase;OK/SW-cl.86;Phosphoribosylaminoimidazolecarboxamide formyltransferase;Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase;PUR9_HUMAN;PURH.
Organism-1
Human
基因ID-1
471
SwissProt-1
P31939
Organism-2
Mouse
SwissProt-2
Q9CWJ9
背景
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009],
细胞定位
mitochondrion,cytosol,cell-cell adherens junction,membrane,extracellular exosome,
