FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CKMT1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
47kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human CKMT1 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of CKMT1 and does not cross-react with related proteins.
基因名称
ckmt1b
别名
Acidic type mitochondrial creatine kinase;CKMT;CKMT1;CKMT1A;CKMT1B;Creatine kinase mitochondrial 1 ubiquitous;Creatine kinase U type, mitochondrial;Creatine kinase ubiquitous mitochondrial;Creatine kinase, mitochondrial 1;ubiquitous;Creatine kinase, mitochondrial 1A;Creatine kinase, mitochondrial 1B;Mia CK;U MtCK;Ubiquitous mitochondrial creatine kinase;UMTCK.
Organism-1
Human
基因ID-1
1159
SwissProt-1
P12532
Organism-2
Mouse
SwissProt-2
P30275
背景
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mi
细胞定位
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
