- 产品信息
商品描述
靶点-Target
JAK1
反应性
Human,Rat
应用
WB,IF,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:200-1000;ICC 1:200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Jak1 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Jak1 and does not cross-react with related proteins.
基因名称
jak1
别名
JAK 1;JAK 1A;JAK 1B;JAK-1;JAK1;JAK1_HUMAN;JAK1A;JAK1B;Janus kinase 1;a protein tyrosine kinase;Janus kinase 1;JTK3;Tyrosine protein kinase JAK 1;Tyrosine protein kinase JAK1;Tyrosine-protein kinase JAK1.
Organism-1
Human
基因ID-1
3716
SwissProt-1
P23458
Organism-2
Mouse
SwissProt-2
P52332
背景
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
细胞定位
Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.





