- 产品信息
商品描述
靶点-Target
Fyn
反应性
Human,Monkey,Rat,Mouse
应用
WB,ICC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
59kD
推荐稀释比
WB 1:500;ICC 1:50
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Fyn protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Fyn and does not cross-react with related proteins.
基因名称
fyn
别名
C syn protooncogene;Fyn;FYN oncogene related to SRC FGR YES;FYN_HUMAN;MGC45350;OKT3 induced calcium influx regulator;P59 FYN;p59-Fyn;Protein tyrosine kinase fyn;Proto oncogene tyrosine protein kinase fyn;Proto-oncogene c-Fyn;Proto-oncogene Syn;Protooncogene Syn;SLK;Src like kinase;Src yes related novel gene;Src-like kinase;Src/yes related novel;Src/yes related novel gene;SYN;Tyrosine kinase p59fyn T;Tyrosine kinase p59fyn;T;Tyrosine-protein kinase Fyn.
Organism-1
Human
基因ID-1
2534
SwissProt-1
P06241
Organism-2
Mouse
SwissProt-2
P39688
背景
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Nucleus. Cell membrane. Present and active in lipid rafts. Palmitoylation is crucial for proper trafficking.





