FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SAFB1
反应性
Human
应用
WB,ICC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:1000;ICC 1:200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human SAFB1 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of SAFB1 and does not cross-react with related prote
基因名称
safb-1
别名
DKFZp779C1727;glutathione S transferase fusion protein;HAP;HET;HSP27 ERE TATA binding protein;HSP27 ERE-TATA-binding protein;HSP27 estrogen response element-TATA box-binding protein;SAF B;SAF-B1;SAFB 1;SAFB;SAFB1;SAFB1_HUMAN;scaffold attachment factor B1.
Organism-1
Human
基因ID-1
6294
SwissProt-1
Q15424
Organism-2
Mouse
SwissProt-2
D3YXK2
背景
This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript v
细胞定位
Nucleus .
