FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GRB2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Recombinant protein of human GRB2.
特异性
This antibody detects endogenous levels of GRB2 and does not cross-react with related proteins.
基因名称
grb2
别名
Abundant SRC homology;Adapter protein GRB2;ASH;Ash protein;EGFRBP GRB2;Epidermal growth factor receptor binding protein;Epidermal growth factor receptor binding protein GRB2;GRB 2;GRB2 adapter protein;Grb2;GRB2_HUMAN;Grb3 3;Growth factor receptor bound protein 2;Growth factor receptor bound protein 3;Growth factor receptor-bound protein 2;HT027;MST084;MSTP084;NCKAP2;OTTHUMP00000166096;OTTHUMP00000166097;OTTHUMP00000166098;Protein ASH;SEM5;SH2/SH3 adapter GRB2.
Organism-1
Human
基因ID-1
2885
SwissProt-1
P62993
Organism-2
Mouse
SwissProt-2
Q60631
背景
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Endosome . Golgi apparatus .
