FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Cyclin H
反应性
Human
应用
WB,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Cyclin H protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Cyclin H and does not cross-react with related proteins.
基因名称
ccnh
别名
6330408H09Rik;AI661354;AV102684;AW538719;CAK;CAK complex subunit;ccnh;CCNH_HUMAN;CDK activating kinase;CDK activating kinase complex subunit;Cyclin dependent kinase activating kinase;cyclin dependent kinase activating kinase complex subunit;Cyclin H;CyclinH;MO15-associated protein;p34;p36;p37.
Organism-1
Human
基因ID-1
902
SwissProt-1
P51946
Organism-2
Mouse
SwissProt-2
Q61458
背景
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple t
细胞定位
Nucleus.
