FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AMACR
反应性
Rat
应用
WB,ICC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:1000;ICC 1:100
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human AMACR(C-terminus) protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of AMACR(C-terminus) and does not cross-react with related proteins.
基因名称
amacr
别名
2 arylpropionyl CoA epimerase;2 methylacyl CoA racemase;2-methylacyl-CoA racemase;Alpha methylacyl CoA racemase;Alpha methylacyl Coenzyme A racemase;Alpha methylacyl-CoA racemase deficiency, included;Alpha-methylacyl-CoA racemase;Amacr;AMACR deficiency, included;AMACR_HUMAN;CBAS4;Da1-8;Macr 1;Macr1;Methylacyl CoA racemase alpha;P504S;RACE;RM.
Organism-1
Human
基因ID-1
23600
SwissProt-1
Q9UHK6
Organism-2
Mouse
SwissProt-2
O09174
背景
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011],
细胞定位
Peroxisome . Mitochondrion .
