FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IκB-α
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human IkB-alpha(N-terminus) protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of IkB-alpha(N-terminus) and does not cross-react with related proteins.
基因名称
NFKBIA IKBA MAD3 NFKBI
蛋白名称
NF-kappa-B inhibitor alpha
别名
I kappa B alpha;I kappa B alpha;I;Kappa;B;alpha;I;Kappa;B;alpha;I-kappa-B-alpha;IkappaBalpha;IkB-alpha;IKBA;IKBA;IKBA_HUMAN;IKBalpha;MAD 3;MAD 3;MAD3;Major histocompatibility complex enhancer binding protein MAD3;Major histocompatibility complex enhancer binding protein MAD3;Major histocompatibility complex enhancer-binding protein MAD3;NF kappa B inhibitor alpha;NF-kappa-B inhibitor alpha;NFKBI;NFKBI;NFKBIA;NFKBIA;Nuclear factor of kappa light chain gene enhancer in B cells;Nuclear factor of kappa light chain gene enhancer in B cells;Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha;Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha.
Organism-1
Human
基因ID-1
4792
SwissProt-1
P25963
Organism-2
Mouse
SwissProt-2
Q9Z1E3
背景
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],
细胞定位
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. .
