ATP-Citrate Lyase(C-term) mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2601032
- 产品信息
商品描述
靶点-Target
ATP-citrate synthase
反应性
Human,Mouse,Monkey
应用
WB,ICC,FC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
120kD
推荐稀释比
WB 1:1000;ICC 1:150;Flow Cyt 1:100
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human ATP-Citrate Lyase protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of ATP-Citrate Lyase and does not cross-react with related proteins.
基因名称
acly
别名
ACL;Acly;ACLY_HUMAN;ATP citrate;pro-S;lyase;ATP citrate lyase;ATP citrate synthase;ATP-citrate;pro-S-;-lyase;ATP-citrate synthase;ATPcitrate synthase;ATPCL;Citrate cleavage enzyme;CLATP;OTTHUMP00000164773.
Organism-1
Human
基因ID-1
47
SwissProt-1
P53396
Organism-2
Mouse
SwissProt-2
Q91V92
背景
ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],
细胞定位
Cytoplasm, cytosol .





