ATP-Citrate Lyase(C-term) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601032

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商品描述
  • 靶点-Target

    ATP-citrate synthase

  • 反应性

    Human,Mouse,Monkey

  • 应用

    WB,ICC,FC

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    120kD

  • 推荐稀释比

    WB 1:1000;ICC 1:150;Flow Cyt 1:100

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 免疫原

    Purified recombinant human ATP-Citrate Lyase protein fragments expressed in E.coli.

  • 特异性

    This antibody detects endogenous levels of ATP-Citrate Lyase and does not cross-react with related proteins.

  • 基因名称

    acly

  • 别名

    ACL;Acly;ACLY_HUMAN;ATP citrate;pro-S;lyase;ATP citrate lyase;ATP citrate synthase;ATP-citrate;pro-S-;-lyase;ATP-citrate synthase;ATPcitrate synthase;ATPCL;Citrate cleavage enzyme;CLATP;OTTHUMP00000164773.

  • Organism-1

    Human

  • 基因ID-1

    47

  • SwissProt-1

    P53396

  • Organism-2

    Mouse

  • SwissProt-2

    Q91V92

  • 背景

    ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],

  • 细胞定位

    Cytoplasm, cytosol .