FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Smad5
反应性
Human
应用
WB,ICC,FC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:1000;ICC 1:75;Flow Cyt 1:100
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human SMAD5 (C-terminus) protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of SMAD5 (C-terminus) and does not cross-react with related proteins.
基因名称
smad5
别名
DKFZp781C1895;DKFZp781O1323;Dwfc;hSmad 5;hSmad5;JV5 1;JV5-1;MAD homolog 5;MAD mothers against decapentaplegic homolog 5;MAD, mothers against decapentaplegic homolog 5;MADH 5;MADH5;Mothers against decapentaplegic homolog 5;Mothers against DPP homolog 5;MusMLP;SMA and MAD related protein 5;SMAD 5;SMAD family member 5;SMAD mothers against DPP homolog 5;Smad5;Smad5;SMAD5_HUMAN.
Organism-1
Human
基因ID-1
4090
SwissProt-1
Q99717
Organism-2
Mouse
SwissProt-2
P97454
背景
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
细胞定位
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
