- 产品信息
商品描述
靶点-Target
TIF1β
反应性
Human
应用
WB,ICC,IHC,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
110kD
推荐稀释比
WB 1:1000;ICC 1:100
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human KAP1 / TIF1 beta protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of KAP1 / TIF1 beta and does not cross-react with related proteins.
基因名称
trim28
别名
E3 SUMO protein ligase TRIM28;E3 SUMO-protein ligase TRIM28;FLJ29029;KAP 1;KAP-1;KRAB associated protein 1;KRAB interacting protein 1;KRAB-associated protein 1;KRAB-interacting protein 1;KRIP 1;KRIP-1;KRIP1;Nuclear corepressor KAP 1;Nuclear corepressor KAP-1;RING finger protein 96;RNF96;TF1B;TIF1 beta;TIF1-beta;TIF1B;TIF1B_HUMAN;Transcription intermediary factor 1 beta;Transcription intermediary factor 1-beta;TRIM28;Tripartite motif containing 28;tripartite motif containing protein 28;Tripartite motif-containing protein 28.
Organism-1
Human
基因ID-1
10155
SwissProt-1
Q13263
Organism-2
Mouse
SwissProt-2
Q62318
背景
The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Associated with centromeric heterochromatin during cell differentiation through CBX1. .





