FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Fatty Acid Synthase
反应性
Human,Mouse,Rat,Monkey,Bovine
应用
WB,IP,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
273kD
推荐稀释比
WB 1:1000;ICC 1:400;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Fatty Acid Synthase protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Fatty Acid Synthase and does not cross-react with related proteins.
基因名称
fasn
别名
[Acyl-carrier-protein] S acetyltransferase;[Acyl-carrier-protein] S malonyltransferase;3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase;3-oxoacyl-[acyl-carrier-protein] reductase;3-oxoacyl-[acyl-carrier-protein] synthase;Enoyl-[acyl-carrier-protein]
Organism-1
Human
基因ID-1
2194
SwissProt-1
P49327
Organism-2
Mouse
SwissProt-2
P19096
背景
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
