- 产品信息
商品描述
靶点-Target
COX IV
反应性
Human,Mouse,Rat,Hamster,Goat,Monkey
应用
WB,FC,ICC,IP,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
17kD
推荐稀释比
WB 1:1000;ICC 1:150;Flow Cyt 1:100
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
A synthetic peptide corresponding to carboxyl terminal residues of human COX IV
特异性
This antibody detects endogenous levels of COX IV and does not cross-react with related proteins.
基因名称
COX4I1
蛋白名称
Cytochrome c oxidase subunit 4 isoform 1 mitochondrial
别名
AL024441;COX 4;COX IV 1;COX IV;COX IV-1;Cox4;COX41_HUMAN;Cox4a;COX4B;COX4I1;COX4I2;COX4L2;COXIV;Cytochrome c oxidase polypeptide IV;Cytochrome c oxidase subunit 4 isoform 1 mitochondrial;Cytochrome c oxidase subunit 4 isoform 1, mitochondrial;Cytochrome C Oxidase subunit IV;Cytochrome c oxidase subunit IV isoform 1;Cytochrome c oxidase subunit IV isoform 2;lung;Cytochrome c oxydase subunit;dJ857M17.2;MGC105470;MGC72016.
Organism-1
Human
基因ID-1
1327
SwissProt-1
P13073
Organism-2
Mouse
SwissProt-2
P19783
背景
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .





