FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KLF4
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
55/65kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant mouse KLF4 protein fragments expressed in E.coli.
特异性
Transfected Only.
基因名称
klf4
别名
Endothelial Kruppel like zinc finger protein;Epithelial zinc finger protein EZF;EZF;GKLF;Gut-enriched krueppel-like factor;KLF;KLF4;KLF4_HUMAN;Krueppel-like factor 4;Kruppel like factor 4;Epithelial zinc finger protein EZF;Gut enriched Krueppel like factor;Kruppel like factor 4;gut;.
Organism-1
Human
基因ID-1
16600
SwissProt-1
O43474
Organism-2
Mouse
SwissProt-2
Q60793
背景
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],
细胞定位
Nucleus.
