FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HP1γ
反应性
Mouse,Human,Monkey,Hamster,Rat
应用
WB,IF,IP,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:1000;ICC 1:200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human HP1-gamma protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of HP1-gamma and does not cross-react with related proteins.
基因名称
cbx3
别名
CBX 3;CBX3;CBX3_HUMAN;Chromobox homolog 3;HP1 gamma homolog, Drosophila;Chromobox homolog 3;Chromobox protein homolog 3;GAMMA;HECH;Heterochromatin like protein 1;Heterochromatin protein 1 homolog gamma;Heterochromatin protein HP1 gamma;HP1 gamma;HP1 gamma homolog;HP1Hs gamma;Modifier 2 protein.
Organism-1
Human
基因ID-1
11335
SwissProt-1
Q13185
Organism-2
Mouse
SwissProt-2
P23198
背景
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011],
细胞定位
Nucleus . Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). .
