- 产品信息
商品描述
靶点-Target
CARM1
反应性
Human,Mouse
应用
WB,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
63kD
推荐稀释比
WB 1:200-1:500
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human PRMT4/CARM1 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of PRMT4/CARM1 and does not cross-react with related proteins.
基因名称
carm1
别名
carm1;CARM1_HUMAN;Coactivator associated arginine methyltransferase 1;Coactivator-associated arginine methyltransferase 1;Histone arginine methyltransferase CARM 1;Histone arginine methyltransferase CARM1;Histone-arginine methyltransferase CARM1;PRMT 4;PRMT4;Protein arginine methyltransferase;Protein arginine N methyltransferase 4;Protein arginine N-methyltransferase 4.
Organism-1
Human
基因ID-1
10498
SwissProt-1
Q86X55
Organism-2
Mouse
SwissProt-2
Q9WVG6
背景
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013],
细胞定位
Nucleus . Cytoplasm . Mainly nuclear during the G1, S and G2 phases of the cell cycle (PubMed:19843527). Cytoplasmic during mitosis, after breakup of the nuclear membrane (PubMed:19843527). .





