FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TBL1
反应性
Human
应用
WB,ICC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
58kD
推荐稀释比
WB 1:1000;ICC 1:100
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human TBL1 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of TBL1X and does not cross-react with related proteins.
基因名称
tbl1x
别名
EBI;F box like/WD repeat protein TBL1X;F-box-like/WD repeat-containing protein TBL1X;SMAP 55;SMAP55;TBL 1;TBL 1X;TBL1;TBL1X;TBL1X_HUMAN;Transducin;beta;like 1;Transducin;beta;like 1 X linked;Transducin;beta;like 1X linked;Transducin beta like 1 X linked;Transducin beta like 1X;Transducin beta like 1X protein;Transducin beta like protein 1, X linked;Transducin beta-like protein 1X;Transducin-beta-like protein 1;X-linked.
Organism-1
Human
基因ID-1
6907
SwissProt-1
O60907
Organism-2
Mouse
SwissProt-2
Q9QXE7
背景
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have bee
细胞定位
Nucleus . Colocalized with MECP2 to the heterochromatin foci. .
