FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TFIIB
反应性
Human,Mouse,Rat,Bovine,Chicken,Dog,Pig
应用
WB,IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
35kD
推荐稀释比
WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:100-1:500;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human TFIIB protein fragments expressed in E.coli.
特异性
TFIIB Monoclonal Antibody detects endogenous levels of TFIIB protein.
基因名称
GTF2B
蛋白名称
Transcription initiation factor IIB
别名
GTF2B;TF2B;TFIIB;Transcription initiation factor IIB;General transcription factor TFIIB;S300-II
Organism-1
Human
基因ID-1
2959
SwissProt-1
Q00403
Organism-2
Mouse
基因ID-2
229906
SwissProt-2
P62915
Organism-3
Rat
基因ID-3
81673
SwissProt-3
P62916
背景
general transcription factor IIB(GTF2B) Homo sapiens This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Chromosome . Non-acetylated form colocalizes with DNA in the G0/1, S and G2 phases of the cell cycle, but not during mitosis (PubMed:24441171). Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase, anaphase, and telophase phases of the cell cycle (PubMed:24441171). .
