FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SOCS-3
反应性
Human,Pig
应用
WB,IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
25kD
推荐稀释比
WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human SOCS-3 (N-terminus) protein fragments expressed in E.coli.
特异性
SOCS-3 Monoclonal Antibody detects endogenous levels of SOCS-3 protein.
基因名称
SOCS3
蛋白名称
Suppressor of cytokine signaling 3
别名
SOCS3;CIS3;SSI3;Suppressor of cytokine signaling 3;SOCS-3;Cytokine-inducible SH2 protein 3;CIS-3;STAT-induced STAT inhibitor 3;SSI-3
Organism-1
Human
基因ID-1
9021
SwissProt-1
O14543
Organism-2
Mouse
SwissProt-2
O35718
背景
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008],
细胞定位
intracellular,cytoplasm,cytosol,
