FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Smad5
反应性
Human,Mouse,Rat,Bovine,Chicken,Pig,sheep
应用
WB,IF,Flow Cyt
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
52kD
推荐稀释比
WB 1:1000-1:2000;IF 1:100-1:500;Flow Cyt 1:100-1:200;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Smad5 (C-terminus) protein fragments expressed in E.coli.
特异性
Smad5 Monoclonal Antibody detects endogenous levels of Smad5 protein.
基因名称
SMAD5
蛋白名称
Mothers against decapentaplegic homolog 5
别名
SMAD5;MADH5;Mothers against decapentaplegic homolog 5;MAD homolog 5;Mothers against DPP homolog 5;JV5-1;SMAD family member 5;SMAD 5;Smad5;hSmad5
Organism-1
Human
基因ID-1
4090
SwissProt-1
Q99717
Organism-2
Mouse
基因ID-2
17129
SwissProt-2
P97454
Organism-3
Rat
基因ID-3
59328
SwissProt-3
Q9R1V3
背景
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
细胞定位
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
