- 产品信息
商品描述
靶点-Target
SCP-3
反应性
Human
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
28kD
推荐稀释比
WB 1:1000-1:2000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human SCP-3 protein fragments expressed in E.coli.
特异性
SCP-3 Monoclonal Antibody detects endogenous levels of SCP-3 protein.
基因名称
SYCP3
蛋白名称
Synaptonemal complex protein 3
别名
SYCP3;SCP3;Synaptonemal complex protein 3;SCP-3
Organism-1
Human
基因ID-1
50511
SwissProt-1
Q8IZU3
Organism-2
Mouse
SwissProt-2
P70281
背景
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010],
细胞定位
Nucleus . Chromosome . Chromosome, centromere . It is present in early unpaired cores, in the lateral domains of the synaptonemal complex and in the chromosome cores when they separate at diplotene. It is found axial to the metaphase I chromosomes and in association with pairs of sister centromeres. The centromere-associated protein becomes dissociated from the centromeres at anaphase II and is not found in mitotic metaphase centromeres. .





