FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PRMT6
反应性
Human,Mouse,Rat
应用
WB,IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
42kD
推荐稀释比
WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:100-1:500;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human PRMT6 protein fragments expressed in E.coli.
特异性
PRMT6 Monoclonal Antibody detects endogenous levels of PRMT6 protein.
基因名称
PRMT6
蛋白名称
Protein arginine N-methyltransferase 6
别名
PRMT6;HRMT1L6;Protein arginine N-methyltransferase 6;Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6;Histone-arginine N-methyltransferase PRMT6
Organism-1
Human
基因ID-1
55170
SwissProt-1
Q96LA8
Organism-2
Mouse
基因ID-2
99890
SwissProt-2
Q6NZB1
背景
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011],
细胞定位
Nucleus .
