FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PP5
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
57kD
推荐稀释比
WB 1:1000-1:2000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human PP5 protein fragments expressed in E.coli.
特异性
PP5 Monoclonal Antibody detects endogenous levels of PP5 protein.
基因名称
PPP5C
蛋白名称
Serine/threonine-protein phosphatase 5
别名
PPP5C;PPP5;Serine/threonine-protein phosphatase 5;PP5;Protein phosphatase T;PP-T;PPT
Organism-1
Human
基因ID-1
5536
SwissProt-1
P53041
Organism-2
Mouse
基因ID-2
19060
SwissProt-2
Q60676
Organism-3
Rat
基因ID-3
65179
SwissProt-3
P53042
背景
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011],
细胞定位
Nucleus . Cytoplasm . Cell membrane . Predominantly nuclear (PubMed:15383005). But also present in the cytoplasm (PubMed:15383005). Translocates from the cytoplasm to the plasma membrane in a RAC1-dependent manner (PubMed:19948726). .
