FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PP2AA
反应性
Human,Mouse,Bovine,Chicken,Dog,Pig,Rabbit,Zebrafish
应用
WB,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
36kD
推荐稀释比
WB 1:1000-1:2000;IF 1:100-1:500;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human PP2A-Cα (N-terminus) protein fragments expressed in E.coli.
特异性
PP2A-Cα Monoclonal Antibody detects endogenous levels of PP2A-Cα protein.
基因名称
PPP2CA
蛋白名称
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
别名
PPP2CA;Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;PP2A-alpha;Replication protein C;RP-C
Organism-1
Human
基因ID-1
5515
SwissProt-1
P67775
Organism-2
Mouse
基因ID-2
19052
SwissProt-2
P63330
Organism-3
Rat
SwissProt-3
P63331
背景
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . In prometaphase cells, but not in anaphase cells, localizes at centromeres (PubMed:16541025). During mitosis, also found at spindle poles (PubMed:16541025). Centromeric localization requires the presence of SGO2 (By similarity). .
