FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PP1β
反应性
Human,Mouse,Rat,Chicken,Dog,Pig
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
37kD
推荐稀释比
WB 1:1000-1:2000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human PP1β protein fragments expressed in E.coli.
特异性
PP1β Monoclonal Antibody detects endogenous levels of PP1β protein.
基因名称
PPP1CB
蛋白名称
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
别名
PPP1CB;Serine/threonine-protein phosphatase PP1-beta catalytic subunit;PP-1B;PPP1CD
Organism-1
Human
基因ID-1
5500
SwissProt-1
P62140
Organism-2
Mouse
基因ID-2
19046
SwissProt-2
P62141
Organism-3
Rat
基因ID-3
25594
SwissProt-3
P62142
背景
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Nucleus, nucleoplasm . Nucleus, nucleolus . Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles. .
