FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Oct-3/4
反应性
Human
应用
WB,Flow Cyt,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
39kD
推荐稀释比
WB 1:1000-1:2000;Flow Cyt 1:100-1:200;IF 1:100-1:500;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Oct-3/4 protein fragments expressed in E.coli.
特异性
Oct-3/4 Monoclonal Antibody detects endogenous levels of Oct-3/4 protein.
基因名称
POU5F1
蛋白名称
POU domain class 5 transcription factor 1
别名
POU5F1;OCT3;OCT4;OTF3;POU domain;class 5, transcription factor 1;Octamer-binding protein 3;Oct-3;Octamer-binding protein 4;Oct-4;Octamer-binding transcription factor 3;OTF-3
Organism-1
Human
基因ID-1
5460
SwissProt-1
Q01860
Organism-2
Mouse
SwissProt-2
P20263
背景
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013],
细胞定位
Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. .
