FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Mi2-α
反应性
Human,Mouse,Rat,Bovine,Dog,Pig
应用
WB,IHC,IF,Flow Cyt
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
227kD
推荐稀释比
WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:100-1:500;Flow Cyt 1:100-1:200;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Mi2-α (C-terminus) protein fragments expressed in E.coli.
特异性
Mi2-α Monoclonal Antibody detects endogenous levels of Mi2-α protein.
基因名称
CHD3
蛋白名称
Chromodomain-helicase-DNA-binding protein 3
别名
CHD3;Chromodomain-helicase-DNA-binding protein 3;CHD-3;ATP-dependent helicase CHD3;Mi-2 autoantigen 240 kDa protein;Mi2-alpha;Zinc finger helicase;hZFH
Organism-1
Human
基因ID-1
1107
SwissProt-1
Q12873
背景
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus, PML body . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with centrosomes in interphase and mitosis. .
