FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Integrin α6
反应性
Human,Mouse,Rat,Bovine,Dog,Pig
应用
WB,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
127kD
推荐稀释比
WB 1:1000-1:2000;IF 1:100-1:500;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Integrin α6 (N-terminus) protein fragments expressed in E.coli.
特异性
Integrin α6 Monoclonal Antibody detects endogenous levels of Integrin α6 protein.
基因名称
ITGA6
蛋白名称
Integrin alpha-6
别名
ITGA6;Integrin alpha-6;CD49 antigen-like family member F;VLA-6;CD antigen CD49f
Organism-1
Human
基因ID-1
3655
SwissProt-1
P23229
Organism-2
Mouse
SwissProt-2
Q61739
背景
integrin subunit alpha 6(ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor .
