FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Integrin α5
反应性
Human,Mouse,Rat,Bovine
应用
WB,Flow Cyt
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
115kD
推荐稀释比
WB 1:1000-1:2000;Flow Cyt 1:100-1:200;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Integrin α5 (N-terminus) protein fragments expressed in E.coli.
特异性
Integrin α5 Monoclonal Antibody detects endogenous levels of Integrin α5 protein.
基因名称
ITGA5
蛋白名称
Integrin alpha-5
别名
ITGA5;FNRA;Integrin alpha-5;CD49 antigen-like family member E;Fibronectin receptor subunit alpha;Integrin alpha-F;VLA-5;CD antigen CD49e
Organism-1
Human
基因ID-1
3678
SwissProt-1
P08648
Organism-2
Mouse
基因ID-2
16402
SwissProt-2
P11688
背景
integrin subunit alpha 5(ITGA5) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],
细胞定位
Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .
