- 产品信息
商品描述
靶点-Target
Fyb
反应性
Human,Rat
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
85kD
推荐稀释比
WB 1:1000-1:2000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Fyb protein fragments expressed in E.coli.
特异性
Fyb Monoclonal Antibody detects endogenous levels of Fyb protein.
基因名称
FYB
蛋白名称
FYN-binding protein
别名
FYB;SLAP130;FYN-binding protein;Adhesion and degranulation promoting adaptor protein;ADAP;FYB-120/130;p120/p130;FYN-T-binding protein;SLAP-130;SLP-76-associated phosphoprotein
Organism-1
Human
基因ID-1
2533
SwissProt-1
O15117
Organism-2
Mouse
SwissProt-2
O35601
背景
The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
细胞定位
Cytoplasm . Nucleus . Cell junction . Colocalizes with TMEM47 at cell-cell contacts in podocytes. .





