- 产品信息
商品描述
靶点-Target
Ep-CAM
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
35kD
推荐稀释比
WB 1:1000-1:2000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human EP-CAM (N-terminus) protein fragments expressed in E.coli.
特异性
EP-CAM Monoclonal Antibody detects endogenous levels of EP-CAM protein.
基因名称
EPCAM
蛋白名称
Epithelial cell adhesion molecule
别名
EPCAM;GA733-2;M1S2;M4S1;MIC18;TACSTD1;TROP1;Epithelial cell adhesion molecule;Ep-CAM;Adenocarcinoma-associated antigen;Cell surface glycoprotein Trop-1;Epithelial cell surface antigen;Epithelial glycoprotein;EGP;Epithelial gly
Organism-1
Human
基因ID-1
4072
SwissProt-1
P16422
Organism-2
Mouse
基因ID-2
17075
SwissProt-2
Q99JW5
背景
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008],
细胞定位
Lateral cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Colocalizes with CLDN7 at the lateral cell membrane and tight junction. .





