FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Cyclin H
反应性
Human,Mouse,Rat,Dog,Pig
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
38kD
推荐稀释比
WB 1:1000-1:2000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Cyclin H protein fragments expressed in E.coli.
特异性
Cyclin H Monoclonal Antibody detects endogenous levels of Cyclin H protein.
基因名称
CCNH
蛋白名称
Cyclin-H
别名
CCNH;Cyclin-H;MO15-associated protein;p34;p37
Organism-1
Human
基因ID-1
902
SwissProt-1
P51946
Organism-2
Mouse
基因ID-2
66671
SwissProt-2
Q61458
Organism-3
Rat
基因ID-3
84389
SwissProt-3
Q9R1A0
背景
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple t
细胞定位
Nucleus.
