- 产品信息
商品描述
靶点-Target
COX4I2
反应性
Human
应用
WB,Flow Cyt,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
20kD
推荐稀释比
WB 1:1000-1:2000;Flow Cyt 1:100-1:200;IF 1:100-1:500;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human COX4I2 (C-terminus) protein fragments expressed in E.coli.
特异性
COX4I2 Monoclonal Antibody detects endogenous levels of COX4I2 protein.
基因名称
COX4I2
蛋白名称
Cytochrome c oxidase subunit 4 isoform 2 mitochondrial
别名
COX4I2;COX4L2;Cytochrome c oxidase subunit 4 isoform 2;mitochondrial;Cytochrome c oxidase subunit IV isoform 2;COX IV-2
Organism-1
Human
基因ID-1
84701
SwissProt-1
Q96KJ9
Organism-2
Mouse
SwissProt-2
Q91W29
背景
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .





