ATP-citrate synthase Monoclonal Antibody
活动价:
市场价:¥1280.00
- 50μL
FAB2600915
- 产品信息
商品描述
靶点-Target
ATP-citrate synthase
反应性
Human,Mouse,Rat,Bovine,Chicken,Pig,sheep
应用
WB,IF,Flow Cyt
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
121kD
推荐稀释比
WB 1:1000-1:2000;IF 1:100-1:500;Flow Cyt 1:100-1:200;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human ATP-citrate synthase (C-terminus) protein fragments expressed in E.coli.
特异性
ATP-citrate synthase Monoclonal Antibody detects endogenous levels of ATP-citrate synthase protein.
基因名称
ACLY
蛋白名称
ATP-citrate synthase
别名
ACLY;ATP-citrate synthase;ATP-citrate;pro-S-;-lyase;ACL;Citrate cleavage enzyme
Organism-1
Human
基因ID-1
47
SwissProt-1
P53396
Organism-2
Mouse
基因ID-2
104112
SwissProt-2
Q91V92
Organism-3
Rat
基因ID-3
24159
SwissProt-3
P16638
背景
ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],
细胞定位
Cytoplasm, cytosol .





