FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ACE
反应性
Human,Mouse,Rat,Bovine
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
150kD
推荐稀释比
WB 1:1000-1:2000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human ACE1 (N-terminus) protein fragments expressed in E.coli.
特异性
ACE1 Monoclonal Antibody detects endogenous levels of ACE1 protein.
基因名称
ACE
蛋白名称
Angiotensin-converting enzyme
别名
ACE;DCP;DCP1;Angiotensin-converting enzyme;ACE;Dipeptidyl carboxypeptidase I;Kininase II;CD antigen CD143
Organism-1
Human
基因ID-1
1636
SwissProt-1
P12821
Organism-2
Mouse
基因ID-2
11421
SwissProt-2
P09470
Organism-3
Rat
基因ID-3
24310
SwissProt-3
P47820
背景
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010],
细胞定位
[Angiotensin-converting enzyme, soluble form]: Secreted.; Cell membrane; Single-pass type I membrane protein. Cytoplasm . Detected in both cell membrane and cytoplasm in neurons. .
