FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Troponin I-FS
反应性
Human
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
21kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Troponin I-FS expressed in E. Coli.
特异性
Troponin I-FS Monoclonal Antibody detects endogenous levels of Troponin I-FS protein.
基因名称
TNNI2
蛋白名称
Troponin I fast skeletal muscle
别名
TNNI2;Troponin I;fast skeletal muscle;Troponin I, fast-twitch isoform
Organism-1
Human
基因ID-1
7136
SwissProt-1
P48788
Organism-2
Mouse
SwissProt-2
P13412
背景
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced trans
细胞定位
nucleus,cytosol,troponin complex,
