FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Troponin I-C
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
24kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of Troponin I-C expressed in E. Coli.
特异性
Troponin I-C Monoclonal Antibody detects endogenous levels of Troponin I-C protein.
基因名称
TNNI3
蛋白名称
Troponin I cardiac muscle
别名
TNNI3;TNNC1;Troponin I;cardiac muscle;Cardiac troponin I
Organism-1
Human
基因ID-1
7137
SwissProt-1
P19429
Organism-2
Mouse
SwissProt-2
P48787
背景
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008],
细胞定位
cytosol,troponin complex,sarcomere,
