FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TORC3
反应性
Human,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
67kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human TORC3 expressed in E. Coli.
特异性
TORC3 Monoclonal Antibody detects endogenous levels of TORC3 protein.
基因名称
CRTC3
蛋白名称
CREB-regulated transcription coactivator 3
别名
CRTC3;TORC3;CREB-regulated transcription coactivator 3;Transducer of regulated cAMP response element-binding protein 3;TORC-3;Transducer of CREB protein 3
Organism-1
Human
基因ID-1
64784
SwissProt-1
Q6UUV7
Organism-2
Mouse
SwissProt-2
Q91X84
背景
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012],
细胞定位
Nucleus . Cytoplasm . Appears to be mainly nuclear (PubMed:15454081). Translocates to the nucleus following adenylyl cyclase or MAP kinase activation (PubMed:30611118). .
