FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Thioredoxin
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
12kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fusion protein with Thioredoxin tag.
特异性
Thioredoxin Monoclonal Antibody detects endogenous levels of Thioredoxin protein.
基因名称
TXN
蛋白名称
Thioredoxin
别名
TXN;TRDX;TRX;TRX1;Thioredoxin;Trx;ATL-derived factor;ADF;Surface-associated sulphydryl protein;SASP
Organism-1
Human
基因ID-1
7295
SwissProt-1
P10599
Organism-2
Mouse
SwissProt-2
P10639
背景
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Nucleus . Cytoplasm . Secreted . Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947). .
