FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TBX5
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
58kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of TBX5 expressed in E. Coli.
特异性
TBX5 Monoclonal Antibody detects endogenous levels of TBX5 protein.
基因名称
TBX5
蛋白名称
T-box transcription factor TBX5
别名
TBX5;T-box transcription factor TBX5;T-box protein 5
Organism-1
Human
基因ID-1
6910
SwissProt-1
Q99593
Organism-2
Mouse
SwissProt-2
P70326
背景
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Shuttles between the cytoplasm and the nucleus. Acetylation at Lys-339 promotes nuclear retention. .
