FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TBL1X
反应性
Human,Monkey
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
62kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human TBL1X expressed in E. Coli.
特异性
TBL1X Monoclonal Antibody detects endogenous levels of TBL1X protein.
基因名称
TBL1X
蛋白名称
F-box-like/WD repeat-containing protein TBL1X
别名
TBL1X;TBL1;F-box-like/WD repeat-containing protein TBL1X;SMAP55;Transducin beta-like protein 1X;Transducin-beta-like protein 1;X-linked
Organism-1
Human
基因ID-1
6907
SwissProt-1
O60907
Organism-2
Mouse
SwissProt-2
Q9QXE7
背景
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have bee
细胞定位
Nucleus . Colocalized with MECP2 to the heterochromatin foci. .
