- 产品信息
商品描述
靶点-Target
SRA1
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
24kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of SRA1 expressed in E. Coli.
特异性
SRA1 Monoclonal Antibody detects endogenous levels of SRA1 protein.
基因名称
SRA1
蛋白名称
Steroid receptor RNA activator 1
别名
SRA1;PP7684;Steroid receptor RNA activator 1;Steroid receptor RNA activator protein;SRAP
Organism-1
Human
基因ID-1
10011
SwissProt-1
Q9HD15
Organism-2
Mouse
SwissProt-2
Q80VJ2
背景
Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA. [provided by RefSeq, Mar 2012],
细胞定位
Nucleus . Cytoplasm .





