FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SOD-1
反应性
Human,Mouse
应用
WB,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
16kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human SOD-1 expressed in E. Coli.
特异性
SOD-1 Monoclonal Antibody detects endogenous levels of SOD-1 protein.
基因名称
SOD1
蛋白名称
Superoxide dismutase [Cu-Zn]
别名
SOD1;Superoxide dismutase [Cu-Zn];Superoxide dismutase 1;hSod1
Organism-1
Human
基因ID-1
6647
SwissProt-1
P00441
Organism-2
Mouse
基因ID-2
20655
SwissProt-2
P08228
背景
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Mitochondrion . Nucleus . Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria. .
