- 产品信息
商品描述
靶点-Target
Smad6
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
53kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Smad6 expressed in E. Coli.
特异性
Smad6 Monoclonal Antibody detects endogenous levels of Smad6 protein.
基因名称
SMAD6
蛋白名称
Mothers against decapentaplegic homolog 6
别名
SMAD6;MADH6;Mothers against decapentaplegic homolog 6;MAD homolog 6;Mothers against DPP homolog 6;SMAD family member 6;SMAD 6;Smad6;hSMAD6
Organism-1
Human
基因ID-1
4091
SwissProt-1
O43541
Organism-2
Mouse
SwissProt-2
O35182
背景
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014],
细胞定位
Nucleus .





